GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UVM | cis | rs11190604 | 1 | rs2495754 | chr10:102324812 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs2495755 | chr10:102324649 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs2495758 | chr10:102321900 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs2495760 | chr10:102318771 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs2502757 | 1 | rs2502757 | chr9:136586954 | SARDH | chr9:136528686-136605077:- | -0.46 | -5.47 | 1.15E-6 | Asthma |
| UVM | cis | rs10461617 | 1 | rs252887 | chr5:56166188 | C5orf35 | chr5:56205103-56213010:+ | 0.95 | 6.93 | 4.86E-9 | Type 2 diabetes |
| UVM | cis | rs10461617 | 1 | rs252898 | chr5:56188931 | C5orf35 | chr5:56205103-56213010:+ | 0.96 | 6.57 | 1.87E-8 | Type 2 diabetes |
| UVM | cis | rs10461617 | 1 | rs252902 | chr5:56116085 | C5orf35 | chr5:56205103-56213010:+ | 0.95 | 6.93 | 4.86E-9 | Type 2 diabetes |
| UVM | cis | rs10461617 | 1 | rs252904 | chr5:56118733 | C5orf35 | chr5:56205103-56213010:+ | 0.95 | 6.93 | 4.86E-9 | Type 2 diabetes |
| UVM | cis | rs10461617 | 1 | rs252909 | chr5:56121131 | C5orf35 | chr5:56205103-56213010:+ | 0.95 | 6.93 | 4.86E-9 | Type 2 diabetes |
| UVM | cis | rs10461617 | 1 | rs252910 | chr5:56192983 | C5orf35 | chr5:56205103-56213010:+ | 0.96 | 6.57 | 1.87E-8 | Type 2 diabetes |
| UVM | cis | rs10461617 | 1 | rs252915 | chr5:56121754 | C5orf35 | chr5:56205103-56213010:+ | -0.95 | -6.93 | 4.86E-9 | Type 2 diabetes |
| UVM | cis | rs10461617 | 1 | rs252916 | chr5:56121788 | C5orf35 | chr5:56205103-56213010:+ | 0.95 | 6.93 | 4.86E-9 | Type 2 diabetes |
| UVM | cis | rs10461617 | 1 | rs252919 | chr5:56124111 | C5orf35 | chr5:56205103-56213010:+ | 0.95 | 6.93 | 4.86E-9 | Type 2 diabetes |
| UVM | cis | rs10461617 | 1 | rs252921 | chr5:56137787 | C5orf35 | chr5:56205103-56213010:+ | 0.95 | 6.34 | 4.59E-8 | Type 2 diabetes |